Phosphodiesterase type 5 is inhibited by Fildena in order to function. More cGMP causes the smooth muscles in the penile blood arteries to relax, increasing the amount of blood that enters the penis. An erection is the outcome of this increased blood flow. Fildena promotes prolonged relaxation of the smooth muscles and enhanced blood flow by blocking PDE-5, which helps maintain higher levels of cGMP in the penis. During sexual stimulation, this process is necessary to get and keep an erection. You may take one pill with or without food and water, however taking Fildena with meals might lessen symptoms like dyspepsia and nausea.